Ferguson is currently leading the JLT Sheffield Shield run-scorers list with 222 runs at 74.00, after scoring a century in his 100th game for South Australia in the draw against Victoria.
"We're desperately keen to get the first win on the board of the season over in Perth," he said.
"We know the WACAs are a fantastic side. They'll come hard after a bad loss to New South Wales and 'JL' (WA coach Justin Langer) will have them up and about.
"We've got a real contest on our hands going over there, but we're really confident."
Ferguson: "It's been a good start to the season and I felt like I was in good control in the middle with Lehmo in our last game." pic.twitter.com/KtfOne3M0p— West End Redbacks (@WestEndRedbacks) November 9, 2017
An unchanged 12 will travel to Perth for the match starting on Monday.
South Australia’s main selection issue before the match is likely to be deciding which of the five selected bowlers will be 12th man.
SA squad: Travis Head (c), Callum Ferguson, Alex Carey, Tom Cooper, John Dalton, Jake Lehmann, Joe Mennie, Kane Richardson, Chadd Sayers, Jake Weatherald, Daniel Worrall, Adam Zampa.
The game starts at 10:30am (local) at the WACA on Monday.
Session 1: 10:30am - 12:30pm
Session 2: 1:10pm - 3:10pm
Session 3: 3:30pm - 5:00pm